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Stem cell trial halted

first_img Share Share Sharing is caring! 10 Views   no discussions HealthLifestyle Stem cell trial halted by: – November 15, 2011center_img Share Embryonic stem cellsThe world’s first official trial using human embryonic stem cells in patients has been halted.Geron, based in California, made the sudden announcement that it was halting further work in this field.In a statement the company said in the “current environment of capital scarcity and uncertain economic conditions” it had decided to concentrate instead on developing cancer treatments.Geron said it was seeking partners to enable further development of its stem cell programmes. The press statement implies the decision is purely a financial one – by stopping its stem cell programme it will cut its workforce by more than a third and save millions of dollars.But the company has already invested tens of millions in the stem cell therapy over the past decade. Its submission to the US Food and Drug Administration to conduct the first trial in patients of human embryonic stem cells was the largest and most complex ever submitted. Geron had injected stem cells into the spine of a small number of spinal patients to test safety. In its statement the company said the treatment had been “well tolerated with no serious adverse events”.The decision does seem to be extraordinary given the huge investment of time and resources. When I visited Geron nearly three years ago, the then chief executive Dr Tom Okarma claimed the technology had an incredible future (Green light for US stem cell work):“What stem cells promise for a heart attack or spinal cord injury or diabetes is that you go to the hospital, you receive these cells and you go home with a repaired organ, that has been repaired by new heart cells or new new nerve cells or new islet cells that have been made from embryonic stem cells.” If that future exists, it won’t be Geron that will now lead the way.Ben Sykes, Executive Director of the UK National Stem Cell Network, said: “Stem cell research continues to show great promise in helping many people currently suffering from incurable conditions and injuries. It is disappointing that Geron has taken the decision to stop its spinal cord injury trial but we hope that the company is able to find new partners who can take on the work and provide the necessary finance.”Joanna Knott, Co-Founder and Chair of SpinalCure Australia said: “This is incredibly sad and frustrating news for people with spinal injuries and their families. It is devastating for those people who will have a spinal injury and may as a result of this research been cured.Daniel Heumann, who is on the board of the Christopher and Dana Reeve Foundation, was more forthright in The Washington Post online which reported him as saying: “I’m disgusted. It makes me sick. To get people’s hopes up and then do this for financial reasons is despicable. They’re treating us like lab rats.”John Martin, Professor of Cardiovascular Medicine at University College London said: “The Geron trial had no real chance of success because of the design and the disease targeted. It was an intrinsically flawed study. And for that reasons we should not be describing this as a set back. “The first trials of stem cell that will give an answer are our own in the heart. The heart is an organ that can give quantitative data of quality.”Josephine Quintavalle from the group Comment on Reproductive Ethics said: “At long last after 10 years of unremitting hype, reality has caught up with embryonic stem cell claims. If Geron is abandoning this project it is because it is simply not working, despite the millions of dollars and hot air that has been invested in the promotion of this research.”Fergus WalshMedical correspondent, BBC News Tweetlast_img read more

10 Capiz LGUs support Anti-Terrorism Bill

first_img“The remaining LGUs are on the process,” he added, noting that coordination efforts have also been made for the support of this province to the measure that is now awaiting the signature of President Rodrigo Duterte. The bill carries provisions imposing life imprisonment without parole on those who will participate in the planning, training, preparation, and facilitation of a terrorist act; possess objects connected with the preparation for the commission of terrorism; or collect or make documents connected with the preparation of terrorism. Based on the record of the Capiz Police Provincial Office (CPPO) as of June 29, the municipalities of Cuartero, Dao, Dumalag, Ivisan, Maayon, Mambusao, Panay, Panitan, Pilar, and Tapaz have expressed support to the bill.“Let us help one another by signifying our support on the manifesto so that we could convey that Capiz is supporting the anti-terrorism bill,” said CPPO-Provincial Operation Management Unit acting chief Major Renante Matillano during a Provincial Peace and Order Council meeting earlier this week.He presented the CPPO’s accomplishments, in the presence of Capiz police director Colonel Julio Gustilo Jr., before the Council members that also included in attendance local chief executives and local government units (LGUs) representatives, among others.According to Matillano, the report will reach Camp Crame and the President will eventually see who among the LGUs have not yet expressed support to the legislation. ROXAS City – Ten towns in this province have shown support to House Bill 6875, or the Anti-Terrorism Act of 2020 which aims to strengthen peace and order in the country.center_img It also calls for 12 years imprisonment to persons who shall threaten to commit terrorism and those who will propose any terroristic acts or incite others to commit terrorism. This province is composed of 16 towns and one component city. (With a report from PIA/PN)last_img read more

L’Equipe: Napoli still negotiating for Osimhen’s teammate Gabriel

first_imgNapoli are not only close to a deal with Lille for Victor Osimhen, but also defender Gabriel Magalhaes for €22m plus bonuses. According to the French newspaper, intensive negotiations have been taking place over the last 24 hours between director of sport Cristiano Giuntoli, Lille President Gerard Lopez and various agents and intermediaries. They proved fruitful, as not only is Osimhen reportedly on the verge of accepting the transfer after initially rejecting this move, but Napoli are also close to defender Gabriel. The Brazilian is targeted by Arsenal and Everton too, but Napoli seems to be having the upper hand.Advertisement read also:Everton, Chelsea face fresh battle for Lille defender Gabriel A transfer can be done for €22m plus bonuses, taking the fee up to €25m. With Osimhen valued at €81m, it’s believed Adam Ounas will be included to Lille as part of the package to lower the overall cost of the operation. FacebookTwitterWhatsAppEmail分享 Loading… center_img Promoted Content8 Superfoods For Growing Hair Back And Stimulating Its Growth20 Historical Things You Won’t Believe Actually HappenedWho Earns More Than Ronaldo?A Guy Turns Gray Walls And Simple Bricks Into Works Of ArtYou’ve Only Seen Such Colorful Hairdos In A Handful Of Anime6 Great Ancient Mysteries That Make China Worth VisitingPlaying Games For Hours Can Do This To Your Body10 Risky Jobs Some Women Do6 Extreme Facts About HurricanesEver Thought Of Sleeping Next To Celebs? This Guy Will Show YouWhich Country Is The Most Romantic In The World?7 Universities In The World Where Education Costs Too Muchlast_img read more

Cabaye content at Newcastle

first_img The France international has been linked with a series of potential suitors after a difficult second season in English football, but is adamant that he is content where he is and that all that matters currently is the fight for Barclays Premier League survival. Cabaye told the Chronicle: “I have three years’ contract left and now my mind is just to save the club. We have two cup finals then it will be the holidays. But I am at Newcastle. I don’t want to think about the future with two games left. I am very, very happy to play for this club and these fans.” Newcastle midfielder Yohan Cabaye has insisted he remains happy on Tyneside despite fevered speculation that his future could lie elsewhere. The scrap to preserve the Magpies’ top-flight status continues at relegated QPR on Sunday, when a point would be good enough to keep them up should FA Cup finalists Wigan lose at Arsenal on Tuesday. Even then, serious questions would have to be asked during the closed-season after a campaign which Cabaye admits has been nowhere near good enough. He said: “We all made some mistakes at the start of the season – that’s why we are fighting for relegation. “But if we learn from our mistakes, no problem. We are only human and we all make mistakes, but now is time to learn and prepare. “We need to finish strongly and then prepare well for next season. We have to be ready to fight and play and be ready again in the Premier League, like we were last season.” center_img Press Associationlast_img read more

England don’t Care about O’Driscoll

first_img The decisive moment of a compelling encounter arrived with Danny Care’s 57th minute try, enabling Stuart Lancaster’s men to turn a 10-6 deficit into a 13-10 lead that they never relinquished. O’Driscoll, making a record-equalling 139th Test appearance ahead of his looming retirement at the end of the season, stood with hands on his hips in frustration as Care dashed over. Seventeen phases passed as the Irish defence came under pressure, but when England went wide in search of the try they blundered, Owen Farrell delaying his pass to Billy Twelvetrees which reduced the space available. The whitewash still beckoned for Jonny May only for the Gloucester wing to drop the ball over the line following a double tackle from Andrew Trimble and Conor Murray. A breathless first quarter continued to unfold at breakneck speed and now it was Ireland who poured forward, going inches close twice through Trimble after quick hands in the backs. An impressive start from the Irish gave way to a renewed attack from England, although their efforts lacked the imagination and skill displayed by their opponents. Farrell conceded a penalty for a late tackle on Murray as the move died out, but once that had been defended the Saracens fly-half landed the first points of the match in the 23rd minute. The frantic pace finally slowed in the second quarter, but Ireland were still looking to put as much speed on the ball as possible when they attacked. Seizing the opportunity to drain the stamina of tighthead David Wilson, who has been limited to just 47 minutes of rugby in two months because of a calf injury, they opted for a series of scrums. Having attempted to soften up England at the set piece, they probed out wide on the left on two occasions, but the defence to keep Dave Kearney wrapped up was superb. Farrell struck the left post with a second penalty attempt before England suffered a damaging blow when Billy Vunipola fell awkwardly on his right ankle and had to be replaced by Ben Morgan. Captain Chris Robshaw made a brave call with a minute of the first half remaining, opting for touch instead of taking a long-range shot at goal and the gamble failed when Luther Burrell knocked on. Just 82 seconds after the interval Ireland raced ahead when Jamie Heaslip sent Rob Kearney darting through a hole at the breakdown on the 22 and the Leinster full-back easily evaded Brown. The gap in England’s defence was compounded by the fact it was tight five forwards Wilson and Joe Launchbury who attempted to close the space and there was only one winner when Heaslip teed up Rob Kearney. Sexton converted and added a penalty, but the deficit was slashed to four points by Farrell following a great passage of play from the Red Rose that almost saw Burrell squeeze over. The pivotal moment arrived 16 minutes into the second half with an outstanding try launched by Robshaw’s break through the midfield. Robshaw fed Harlequins team-mate Brown and just as the full-back was hauled down, Care grabbed his pass and raced in under the posts with Farrell converting. England needed to summon on their depths of character as they repelled a driving maul that showed Ireland were far from finished as an attacking force. Dave Kearney tripped as Ireland staged one final attack and once more the home defence held firm, snuffing out the final throws of Irish resistance. The 35-year-old’s 13th and final appearance against England ended in bitter disappointment as Ireland’s Triple Crown and Grand Slam ambitions evaporated with their first defeat of the Championship. When Rob Kearney capitalised on slack defending to touch down under the posts, the Irish had established a commanding position underpinned by a 10-3 lead. But the Red Rose rallied with a display of trademark character to register their fourth successive victory in the fixture. Remarkably, the score had been limited to just 3-0 in England’s favour at half-time as defences reigned, the rivals taking it in turns to trade blows in an absorbing contest. Ireland’s starting XV contained 422 more caps at 724, but it was panic-free England who looked the grizzled band of proven veterans in a nerve-shredding final quarter. With two rounds of the Six Nations remaining, England, Ireland, France and Wales remain in contention for the title with Twickenham hosting Warren Gatland’s defending champions next on March 9. For the second successive game the magnificent Mike Brown was named man of the match with his run to set up Care’s try the high point of another outstanding afternoon. The Harlequins full-back was influential as England made a bulldozing start, producing a diving catch off O’Driscoll’s chip and then speeding free from the breakdown. England ruined Brian O’Driscoll’s Twickenham farewell and created a four-way shootout for the RBS 6 Nations title after ending Ireland’s Grand Slam quest. Press Associationlast_img read more

Pollard springs to life as Strikers silence Thunder

first_imgSYDNEY Thunder needed a win to remain alive in the Big Bash League, but a crushing 77-run defeat to Adelaide Strikers ended their hopes.Kieron Pollard smashed five sixes in a 22-ball 47 as the Adelaide Strikers ended Sydney Thunder’s hopes of reaching the Big Bash League semi-finals with a 77-run victory yesterday.The Strikers came into this meeting at the Sydney Showground Stadium bottom of the table, with their own last-four ambitions already over, while the defending champions needed a victory from their final fixture to stay alive in the tournament.But New Zealand leg-spinner Ish Sodhi returned 6-11 – the second best BBL figures behind Lasith Malinga’s 6-7 in 2012 – as the Thunder collapsed to 101 all out after the Strikers had posted 178-5.Ben Dunk became this season’s top run-scorer, overtaking Chris Lynn as the Strikers opener plundered 65 from 40 deliveries, including five fours and three maximums.He had good support from the evergreen Brad Hodge (39 from 32), before Pollard clubbed in his 22-ball 47.Only Shane Watson (39) and Kurtis Patterson (29) reached double figures in reply for the Thunder, as the Strikers gained a consolation win to send the holders to the bottom of the table.West Indian all-rounder Carlos Brathwaite on the other hand had an evening to forget.The Twenty20 captain, with lime green bat in hand lasted only two deliveries as Sodhi ripped through the Thunder batting line-up. Brathwaite had also dropped Dunk when the opener was on eight – the missed chance seeming to spark the electric opener into gear, hitting his first six two balls later and then accelerating to his 50. (Sportsmax.com)last_img read more

No. 7 Duke looks to extend streak vs ND

first_img February 13, 2020 Share This StoryFacebookTwitteremailPrintLinkedinRedditNotre Dame (15-9, 6-7) vs. No. 7 Duke (21-3, 11-2)Cameron Indoor Stadium, Durham, North Carolina; Saturday, 4 p.m. ESTBOTTOM LINE: No. 7 Duke looks for its sixth straight win in the head-to-head series over Notre Dame. In its last five wins against the Fighting Irish, Duke has won by an average of 16 points. Notre Dame’s last win in the series came on March 10, 2016, an 84-79 victory. No. 7 Duke looks to extend streak vs ND Associated Press center_img ___For more AP college basketball coverage: https://apnews.com/Collegebasketball and http://twitter.com/AP_Top25___This was generated by Automated Insights, http://www.automatedinsights.com/ap, using data from STATS LLC, https://www.stats.com ARE YOU EXPERIENCED: Notre Dame has depended on senior leadership this year while Duke has been fueled heavily by freshmen. For the Fighting Irish, seniors John Mooney, T.J. Gibbs, Prentiss Hubb and Juwan Durham have collectively accounted for 65 percent of the team’s scoring, including 81 percent of all points over its last five. In the other locker room, freshmen Vernon Carey Jr., Cassius Stanley, Matthew Hurt and Wendell Moore Jr. have combined to account for 55 percent of Duke’s scoring this season.CREATING OFFENSE: Tre Jones has either made or assisted on 49 percent of all Duke field goals over the last three games. The sophomore guard has accounted for 23 field goals and 16 assists in those games.STREAK STATS: Duke has won its last three home games, scoring an average of 79.3 points while giving up 63.7.ACCOUNTING FOR ASSISTS: The Fighting Irish have recently converted buckets via assists more often than the Blue Devils. Duke has an assist on 38 of 80 field goals (47.5 percent) over its past three outings while Notre Dame has assists on 44 of 71 field goals (62 percent) during its past three games.DID YOU KNOW: Duke is ranked third among all Division I teams with an average of 82.6 points per game.last_img read more

’SC student loan default rate low

first_imgAt 1.6 percent, USC’s student loan default rate stands well below the national average of 8.8 percent, although defaulting on such loans is still a prevalent concern for many students at USC.In the 2009 fiscal year, the cohort default rate, which measures the number of borrowers whose first loan repayments were due between Oct. 1, 2008, and Sept. 30, 2009, among student borrowers rose to 8.8 percent, from 7 percent in the previous year, according to a report released by U.S. Department of Education last week.USC does what it can to ensure its students do not default on their loans, said Thomas McWhorter, executive director of USC Financial Aid.“Students go through federally mandated entrance and exit counseling in addition to USC counseling,” McWhorter said. “And depending on the amount of debt they take on, they can even go through customized counseling.”Rachel King, a senior majoring in psychology, said she was told the value of her education superseded debt.“I’ve always been given the advice to take out what you need and pay back the minimum because education is the most important and you can pay back your loans later,” King said.As defined by the Financial Aid Office, defaulting is the failure to repay a loan, as specified in the loan documents. For federal loans, the specified time period is nine months. If the borrower has not made a payment within this time frame, the lender will declare the loan in default and the remaining balance will be due immediately.Of the 3.6 million borrowers who entered repayment during this time, more than 320,000 defaulted.The percentage of students who defaulted on student loans at private institutions rose from 4 to 4.6 percent, while the percentage of students who defaulted on student loans at public institutions rose from 6 to 7.2 percent.Students who are saddled with debt when they leave college face serious financial hurdles later on in life, said Rich Williams, higher education advocate for the California Public Interest Research Group.“A large debt burden makes life tough for graduates,” Williams said. “Buying a home, starting a family or starting a small business may not be options for some student loan borrowers, even if they have a job. Those who default on their loans have a damaged credit history and could be discriminated against when applying for a job or even renting an apartment.”Shrinking state budgets and stagnant grant aid have shifted much of college tuition costs to students and their families, leading to an increased reliance on student loans, Williams said.Twelve years ago, the average college student graduated with $12,000 of debt. He or she now carries more than $23,000 of debt on average, Williams said.Williams said defaulting on student loans is particularly bad because unlike unsecured debt, such as credit card bills, student loans are nearly impossible to discharge, the cancelling of a loan, even in bankruptcy. He added, however, there are options available to students that have defaulted on student loans.“Once you’ve defaulted, effort is made by the school and government to get you back into paying your debt,” Williams said. “Students can investigate other options that are available to them. The government has increased the number of repayment programs.”Borrowers who have defaulted can either consolidate the loans, allowing students to combine federal student loans to make for easier payments, or rehabilitate the loans, which allows students to reverse their default status.Once the student has forgone default, many more payment plans are available. An income-based repayment program is one option that caps borrower’s required monthly payment at an amount deemed affordable based on a student’s income and family size. Through the Public Sector Loan Forgiveness program, the federal government forgives the loans of students who go on to work in the public sector for at least 10 years.Vanessa Woghiren, a junior majoring in biological sciences, said defaulting on college loans is a serious concern for her.“I receive a lot of financial aid but every year I almost have no choice but to take out the rest in loans,” Woghiren said. “I have to consider that I’ve been doing this every semester and I’m a junior now and a lot will have occurred by the time I graduate.”Steve Moltzen, a senior majoring in business administration, is more focused on a job so that he can pay off his loans in the near future and avoid defaulting.“I’m more concerned about finding a job,” Moltzen said. “If I don’t, defaulting becomes a serious possibility.”last_img read more

Faculty Union charges USC with unfair labor practices

first_imgFaculty at the Dornsife College of Letters, Arts and Sciences have filed charges against USC with the National Labor Relations Board, accusing the University of unfair labor practices and asking for a delay in the upcoming unionization vote.Joseph Chen | Daily TrojanForward march · USC Faculty Forward, a precursor to the Faculty Union, holds a rally on campus in April 2015 to encourage support for higher wages and better benefits for the University’s non-tenure track faculty.In an email sent on Friday afternoon, the USC Faculty Union — a group of non-tenure track faculty working to join the Service Employees International Union Local 721 — stated that USC’s “business model of education” had left them with low wages and few benefits, a problem that could be remedied by joining a labor union.Efforts to unionize, however, have been met with resistance from the University, resulting in the charges that were filed Friday by SEIU Local 721 on behalf of USC faculty, according to the email.Adjunct faculty at the Roski School of Art and Design and the USC International Academy voted to join SEIU Local 721 in February, but the Dornsife vote resulted in a loss for pro-union organizers. However, following an appeal by the USC Faculty Union, the National Labor Relations Board ruled in April that the University’s actions prior to the vote — including a series of emails sent out by Provost Michael Quick, which discouraged faculty members from supporting unionization — made the results of the vote invalid.“Even after a landslide unionization victory in Roski, USC has maintained an aggressive anti-union stance — refusing to recognize the Roski union victory and promising to appeal their union vote to the highest court, flooding the National Labor Relations Board with frivolous appeals aimed at silencing our collective voice,” the Faculty Union wrote in the email. “In Dornsife, the University’s blatant lawbreaking during the unionization process led the Federal government to throw out the election results altogether and call for a new vote.”Andrea Parra, an associate professor in the Department of Spanish and Portuguese and one of the organizers of the Faculty Union, hopes that bringing charges against USC will result in a statement of neutrality from the University, which so far has actively tried to prevent unionization on campus.“[The University’s] campaign of fear and intimidation towards faculty will only intensify if left unchecked — together we are holding the University accountable, and ensuring that faculty can consider the question of unionization through a fair and democratic process free from University interference,” Parra wrote in an email to the Daily Trojan. “Despite our repeated attempts to hold the University accountable for its continued law breaking, University administrators sent out another communication encouraging faculty to vote against the union just last week.”Parra said that USC’s anti-union stance has also contributed to the Faculty Union’s actions against the University.“For instance, USC administration continues to charge that contingent faculty are ‘managers’ due to the service component of their contracts, and are therefore precluded from organizing a union,” Parra said.The Faculty Union has asked that the Dornsife vote be delayed “to protect free and fair elections for workers,” according to the email. The vote was initially supposed to take place within several weeks of the original NLRB ruling in April, but the NLRB will set the new date of the vote if the charges are upheld, according to Parra.The University, however, has stated that the request to delay the vote will not significantly change the outcome and believes that the initial results should be respected.“Local 721 has not told us what charges they filed with the NLRB,” Quick said in an email to the Daily Trojan. “We are acting in good faith and lawfully. We believe Dornsife faculty should have the chance to make their will known. It seems to us that Local 721 would not be trying to block the election if they thought the faculty majority supports them.”The NLRB ruling in April stated that pay raises offered in the week prior to the unionization vote, as well as statements implying that faculty would no longer be able to participate in governance, “[created] a general atmosphere of fear making a free election impossible.” The University has disputed this report on the basis that Quick’s statements about faculty governance were meant to explain to faculty what would occur were they to vote for unionization.last_img read more

Brice Butler is now expected to transfer

first_imgUSC sophomore wide receiver Brice Butler will transfer, according to a story published on ESPNLosAngeles.com Wednesday night.“I’m leaving because I want to play football in the NFL and a big key to that is playing in college,” Butler told ESPNLosAngeles’ Pedro Moura in a text message. “And I feel that after this season that would be a tough task staying here.”Around 11 p.m. Wednesday, Butler announced his decision via Twitter saying, “Always will be a part of trojan nation! No regrets, I just gotta go play fball, which isn’t happening here… I love all y’all! Always will.”Butler had not previously indicated he would transfer.A native of Norcross, Ga., Butler had a promising freshman year in 2009, totaling 20 catches for 292 yards and two touchdowns. He played in all 12 games and started against Stanford, where he caught six passes for 96 yards, including a 36-yard touchdown grab. As a result, he was named to ESPN.com’s All Pac-10 freshman team.Those numbers, however, failed to carry over to 2010, as he was lost among a new coaching staff. Despite playing in 12 of 13 games, he caught just nine passes for 112 yards and one touchdown, as he was behind the likes of fellow receivers Robert Woods, Ronald Johnson and Brandon Carswell.Though Johnson was a senior, Butler would have faced stiff competition from redshirt freshman Kyle Prater, who was a highly rated recruit last year, as well as two incoming freshmen. George Farmer, who is ranked the No. 1 wide receiver and No. 3 prospect overall nationally by Yahoo! Sports’ Rivals.com, and Victor Blackwell, who is ranked 18th nationally for wide receivers by Rivals, both have committed to USC.last_img read more